This reduces dryness and flaking by increasing skin hydration. Used as a topical skincare ingredient, hyaluronic acid is also well tolerated. Healthline Media does not provide medical advice, diagnosis, or treatment. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hyaluronic Acid is a natural polysaccharide found in connective tissues such as cartilage. It’s also possible to experience a rash on and around the injection site. 8  The same could theoretically occur with oral hyaluronic acid, albeit mildly due to the lower dose. Sodium hyaluronate is also an ophthalmic viscosurgical device (OVD). The rise in DEFβ2 also played a role. Hyaluronic Acid – Benefits vs Side Effects Health Guide Products for healthy, younger looking skin have always seemed to be the most sought after when it comes to skin care. It is found in the highest concentration in the joints and eyes. Hyaluronic acid has a high molecular weight, which means it’s a macromolecule. Vitamin E supplements, St. John's Wort, aspirin, nonsteroidal anti-inflammatory drugs such as Aleve and Motrin may increase bruising or bleeding after injection of hyaluronic acid. This shouldn't suggest that oral hyaluronic acid is entirely free of side effects. All rights reserved. Side effects of HA include gastrointestinal discomfort, headaches, ulceration, sleepiness, pain in the joints, loss of appetite. The FDA has approved commercial hyaluronic acid products like Juvederm and Restylane as safe temporary fillers with effects that can last up to one year. In turn, it can improve hydration from the underlying skin layers. There are, however, some occasion hyaluronic acid side effects that are worth knowing. Yes, hyaluronic acid is a hydrator. Here's what you need to know about this magic ingredient. Therefore, patients should stop these drugs at least one … Synvisc vs. Hyalgan: Is There a Difference? What are the side effects of hyaluronic acid? They’re also called artificial tears. What Causes Some Men to Have Dry, Brittle Hair and How to Treat It, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI. Advertising revenue supports our not-for-profit mission. A serum is a product with a high concentration of beneficial ingredients. Read on, to learn about hyaluronic acid side effects and uses. Babies’ skin has almost zero low molecular weight hyaluronic acid. Hyaluronic acid or Hyaluronic sodium is found in the human body naturally. This site complies with the HONcode standard for trustworthy health information: verify here. We include products we think are useful for our readers. Still, it’s possible to be sensitive to any ingredient. Apply firm pressure and ice packs before, after, or during the session in order to minimize both of these adverse effects. Hyaluronic acid is also used for making medicines and is derived from certain bacteria and rooster combs. The hyaluronic acid side effect summary: Low molecular weight hyaluronic acid is involved in activating your skin’s inflammation pathways. You can buy skin care products with sodium hyaluronate at: Shop for products containing sodium hyaluronate online. This article lists the top 7 benefits of…, Glabellar lines (or forehead furrows) are a natural part of aging. In a 2013 study, an HA sodium salt cream reduced symptoms of rosacea in adults. Although not all of these side effects may occur, if they do occur they may need medical attention. Hyaluronic acid is a powerful skincare hydrator. Oral hyaluronic acid may help moisturize the skin and leave it looking smoother and feeling softer. After only 40 days, the group taking the HA oral supplements noticed a significant decrease in skin roughness and wrinkle depths. The treatment is directly injected in the knee, which decreases pain in the area. With oral doses, hylaluronic acid side effects can be much more severe. It’s rarely associated with side effects when applied topically. Hyaluronic acid has the word "acid" in its name, but there's no reason for sensitive skin types to tread lightly — it's safe for everyone. If you don't like the way they look, there are home remedies, clinical treatment…, Castor oil is a common component in some artificial tears solutions. But as sodium hyaluronate hydrates the skin, it improves the appearance of wrinkles. Similarly, in a 2014 study, HA sodium salt gel improved an inflammatory skin disorder called seborrheic dermatitis. Hyaluronic acid is a major ingredient in many medical and anti-aging therapies. In a 2014 study, formulas with sodium hyaluronate decreased wrinkle depth and improved elasticity. Hyaluronic acid supplements can even simply help keep skin better hydrated ( x ). The researchers linked this effect to the hydrating properties of HA. A face wash with sodium hyaluronate can help hydrate your skin while removing makeup, dirt, and excess oil. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Beyond skin care, sodium hyaluronate has other medical benefits. It comes in a bottle with a spray attachment, which you use to mist the liquid into your nostril.Like eye drops, nasal sprays are available at drugstores. You place the drops directly in your eyes. ... It’s rarely associated with side effects when applied topically. Read on to learn how it compares to HA, along with its benefits and uses. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. It can be extracted and used separately. However, not all hyaluronic acid molecules are created equal. This is how hyaluronic acid works, its benefits, and its side effects on every type of skin from dry to oily. As the name suggests, sodium hyaluronate is the sodium salt version. Hyaluronic acid (HA) is a is a lubricating substance produced by the human body. Bruising due to hyaluronic acid This is usually expected along with some inflammation and shouldn’t last more than a few days. And too much inflammation is pro-ageing, it even has a name – inflammaging. If you buy through links on this page, we may earn a small commission. After getting injections, some people notice pain, bruising, itching and swelling. If your hair tends to be dry, you may want to try changing your hair care routine. Using it helps to lubricate the eyes and prevent moisture from leaving the eyes…, Synvisc and Hyalgan are both viscosupplements used to treat osteoarthritis. Hyaluronic acid is a natural substance that is often used as a supplement, serum or in other forms. Eye drops are used to treat dry eyes. For extra caution start slowly, by using your retinol at night once or twice a week and build up use gradually, to avoid side effects like excessive peeling, redness, and … Hyaluronic acid (HA) is a substance that naturally occurs in your body, including your skin and joint fluid. As a derivative of HA, sodium hyaluronate has similar benefits to HA. It’s given by a medical provider in a clinical setting. This is due to its low molecular weight, according to a 2019 report. Sodium hyaluronate is an ingredient that’s extracted from HA. When used as a nasal spray, sodium hyaluronate can relieve symptoms of rhinitis. Sodium hyaluronate is different from HA, though. A case report in Ophthalmic Plastic Reconstruction Surgery reported rare blindness in the eye of a patient receiving injections of HA. On rare occasions, hyaluronic acid can cause allergy. Babies’ skin can quickly heal without scaring. Hyaluronic acid is also used in injectable dermal fillers to help eliminate … Hyaluronic Acid has risen in popularity and has been deemed with claims such as ‘the key to the fountain of youth’. It may be listed as “hyaluronic acid (as sodium hyaluronate)” on skin care labels. Digestive upset, breathing irregularities, and changes in energy or mood are the most severe side effects associated with taking oral hylaluronic acid. According to the researchers, this was due to HA’s ability to promote cell multiplication and tissue repair. You can find it in products like serums, eye creams, and facial cleansers. What are the side effects of hyaluronic acid? Many people report that their skin feels “dewier,” the bags under their eyes become lighter and their skin texture is … The side effects of hyaluronic acid could be immediate, short-term, and medium-term. The large molecules coat the skin and prevent water loss, leading to better hydration. When injected, hyaluronic acid may cause headaches, dizziness, itching, tingling, or swelling. These side effects may go away during treatment as your body adjusts to the medicine. The most common side effects of hyaluronic acid are reactions at the site of injection such as: bruising, redness, pain, itching, tenderness, and ; swelling. Other medical benefits of sodium hyaluronate, Where to get products with sodium hyaluronate, Why Science Says Hyaluronic Acid Is the Holy Grail to Wrinkle-Free, Youthful Hydration, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, How to Minimize and Prevent Glabellar Lines (Also Known as Forehead Furrows), Castor Oil for Dry Eyes: Benefits and Side Effects. Mayo Clinic does not endorse companies or products. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site. The skin near the injection site may also become itchy, or may feel cold or like it’s burning. Like other skin treatments, HA may have side effects. Some side effects include skin necrosis (premature cell death), visual loss, and other complications. However, with benefits come the side effects. Relieve Joint Pain by Keeping Bones Well Lubricated. Powdered vitamin C is thought to be more stable than other forms of vitamin C. Here’s how it works and when you may want to use it. All rights reserved. Restylane (hyaluronic acid) Dermal Filler Injectable Gel is used for mid-to-deep dermal implantation for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds (laugh lines).Restylane is also used for lip augmentation in patients over the age of 21. However, because hyaluronic acid is naturally occurring, side effects are usually limited . In very rare cases, hyaluronic acid can cause an allergic reaction when it comes into contact with the skin. Reactivation of cold sores or fever blisters (herpes simplex) of the lips or area surrounding the lips. Does Hyaluronic Acid Have Any Side Effects? This content does not have an English version. Sodium hyaluronate is part of HA. As an OVD, sodium hyaluronate protects the eye and creates space for surgery. Rosacea is an inflammatory skin condition that causes redness, burning, and bumps. In addition, no side effects were noted ( x ). Note – the supplement form of HA is considered safe for most people. Although not considered a common side effect, hyaluronic acid has caused skin to blister or appear discolored. It’s small enough to penetrate the epidermis, or top layer of the skin. Swelling and bruising. Since sodium hyaluronate is derived from HA, it’s sometimes called “hyaluronic acid.” It may be listed as “hyaluronic acid (as sodium hyaluronate)” on skin care labels. Allergic reactions to hyaluronic acid manifest through the swelling of the face and throat, difficulty … Injectable hyaluronic acid. It’s the sodium salt form of HA. May 25, 2020. The system breaks down food, extracts nutrients…. This content does not have an Arabic version. The New Zealand Dermatological Society reports that hyaluronic acid injections last between three and nine months 1. Our website services, content, and products are for informational purposes only. You may report side effects to the FDA at 1-800-FDA-1088. This is a liquid that contains sodium hyaluronate. DEFβ2 has antimicrobial effects, which protects wounds from infection. Call your doctor for medical advice about side effects. Used as a dermal filler, hyaluronic acid has a slightly longer list of potential side effects. Effects. Here, it attracts moisture and reduces inflammation. When applied topically, it has a moisturizing and soothing effect. Also, drinking alcoholic beverages while taking this supplement is not recommended since alcohol may increase the risk of side effects of HA. Sodium hyaluronate can also soothe skin inflammation. This is important because it changes how the substance affects the skin. These properties, combined with the anti-inflammatory activity of sodium hyaluronate, can help support proper wound healing. A case report in Ophthalmic Plastic Reconstruction Surgery reported rare blindness in the eye of a patient receiving injections of HA. 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